Ananth J
Int Pharmacopsychiatry. 1976;11(4):246-60. doi: 10.1159/000468239.
Psychotropic drugs are used frequently for the treatment of emotional as well as other disorders. With usage so widespread, many pregnant women receive psychotropic drugs. Maternal ingestion of these drugs may produce, in the fetus, side effects including withdrawal symptoms. Withdrawal signs in the fetus as a result of maternal intake of opiates, hypnotics, analgesics, and tricyclic antidepressant drugs have been reported. Fetal side effects can occur by maternal ingestion of nuroleptic medications, lithium, antidepressants, anxiolytic sedatives, anticonvulsants, and bromides. The author feels that even though these drugs are generally safe, they must only be administered to pregnant women when absolutely needed, and then under vigilance.
精神药物常用于治疗情绪及其他紊乱。由于其使用如此广泛,许多孕妇会使用精神药物。母亲摄入这些药物可能会在胎儿身上产生包括戒断症状在内的副作用。已有报道称,母亲摄入阿片类药物、催眠药、镇痛药和三环类抗抑郁药会导致胎儿出现戒断体征。母亲摄入抗精神病药物、锂盐、抗抑郁药、抗焦虑镇静剂、抗惊厥药和溴化物可能会使胎儿产生副作用。作者认为,尽管这些药物通常是安全的,但必须仅在绝对必要时才给孕妇使用,而且使用时要保持警惕。