蛙皮代谢与细胞完整性及电解质转运的关系。
Relation of metabolism of frog skin to cellular integrity and electrolyte transfer.
作者信息
LEVINSKY N G, SAWYER W H
出版信息
J Gen Physiol. 1953 May;36(5):607-15. doi: 10.1085/jgp.36.5.607.
Abstract
- The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mechanism for maintaining intracellular potassium appear to be independent. 3. The xanthines specifically inhibit the sodium transfer mechanism; at higher concentrations, they depress metabolism and cause loss of potassium from the skin.
摘要
- 蛙皮对钠的转运以及维持皮肤细胞内正常的钾水平均依赖于新陈代谢和磷酸键能量的供应。2. 除了对磷酸键能量的共同需求外，钠的转运机制和维持细胞内钾的机制似乎是独立的。3. 黄嘌呤类物质特异性抑制钠转运机制；在较高浓度时，它们会抑制新陈代谢并导致皮肤中的钾流失。
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