维吉尼亚霉素M因子的微生物乙酰化作用
Microbial acetylation of M factor of virginiamycin.
作者信息
De Meester C, Rondelet J
出版信息
J Antibiot (Tokyo). 1976 Dec;29(12):1297-305. doi: 10.7164/antibiotics.29.1297.
PMID:13056
Abstract
The M component of virginiamycin was found to be modified by whole cells or cell-free enzyme preparations of a Staphylococcus aureus strain. It was shown that this reaction proceeds by enzymatic acetylation of the secondary alcoholic function of the molecule, followed by a rapid chemical degradation of the O-acetylated product.
摘要
已发现维吉尼亚霉素的M组分可被一株金黄色葡萄球菌的全细胞或无细胞酶制剂修饰。结果表明，该反应通过分子仲醇功能的酶促乙酰化进行，随后O-乙酰化产物发生快速化学降解。
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