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食物过敏、特应性皮炎与医学中的表皮病变

Food allergy, atopic dermatitis and superficialism in medicine.

作者信息

Cantani A, Lucenti P, Arcese G

机构信息

Dept of Pediatrics, University La Sapienza, Roma.

出版信息

Riv Eur Sci Med Farmacol. 1992 Jul-Aug;14(4):233-6.

PMID:1305997
Abstract

Although the essential immunology underlying atopic diseases is now being clarified, there are still few accountable diagnostic tests. Therefore the recognition and treatment of these diseases continues to be based mainly on clinical skill and, in particular, on the taking of a careful history. This means that the observer bias can be a significant factor, and so whether or not the diagnosis is made may dependent on a clinician's preconceptions. Furthermore, the general interest in the subjects has tended to divided the medical consensus between believers and nonbelievers. In infancy, food allergy has protean manifestations and is provoked by many different food allergens. In addition to the lack of really useful diagnostic tests, there is the difficulty of easily and reliably conducting double-blind challenges in general pediatric practice. Thus it is crucial that a scientific, and critical, approach is adopted and that doctors attentively record the case history and observe the response to elimination diets and challenges. True science has nothing to do with superficialism.

摘要

尽管目前特应性疾病的基本免疫学原理正在逐步明晰,但可靠的诊断测试仍然很少。因此,这些疾病的识别和治疗仍主要基于临床技能,尤其是详细的病史采集。这意味着观察者偏差可能是一个重要因素,诊断是否成立可能取决于临床医生的先入之见。此外,人们对这些主题的普遍关注往往使医学界在相信者和怀疑者之间产生了分歧。在婴儿期,食物过敏有多种表现形式,可由许多不同的食物过敏原诱发。除了缺乏真正有用的诊断测试外,在一般儿科实践中难以轻松、可靠地进行双盲激发试验。因此,采用科学严谨的方法至关重要,医生要认真记录病史,并观察对排除饮食和激发试验的反应。真正的科学与肤浅无关。

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