Bhuripanyo P, Graisopa S, Suwanwatana C, Prasertkaew S, Kiatsayompoo S, Bhuripanyo K, Wangsai W
Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
J Med Assoc Thai. 1992 Oct;75(10):570-7.
We prospectively conducted a hospital based study to determine the prevalence of vascular complications in NIDDM and their risk factors. Using standard protocol for interviewing, physical examination and laboratory investigations, we studied 207 patients from the diabetic clinic and medical outpatient department (ratio 3.9:1) by systematic sampling. The prevalence of hypertension, coronary heart disease cerebrovascular disease, peripheral and large vessel disease was 22.2, 22.2, 8.2, 21.3 and 34.8 per cent respectively. We found that the prevalence of small vessel disease, retinopathy and nephropathy was 34.3, 25.1 and 12.5 per cent respectively. The complications were slightly higher in females and increased with duration of diabetes. By univariate and logistic regression analysis, we found that the risk factors of large vessel disease were body mass index, diastolic blood pressure, duration of diabetes and for small vessel disease were duration of diabetes and high uric acid.
我们前瞻性地开展了一项基于医院的研究,以确定非胰岛素依赖型糖尿病(NIDDM)血管并发症的患病率及其危险因素。我们采用标准的访谈、体格检查和实验室检查方案,通过系统抽样对糖尿病门诊和内科门诊的207例患者进行了研究(比例为3.9:1)。高血压、冠心病、脑血管疾病、外周血管和大血管疾病的患病率分别为22.2%、22.2%、8.2%、21.3%和34.8%。我们发现小血管疾病、视网膜病变和肾病的患病率分别为34.3%、25.1%和12.5%。并发症在女性中略高,并随糖尿病病程的延长而增加。通过单因素和逻辑回归分析,我们发现大血管疾病的危险因素是体重指数、舒张压、糖尿病病程,而小血管疾病的危险因素是糖尿病病程和高尿酸。