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[老年白内障患者血清及晶状体中7种元素的分析]

[Analysis of 7 elements in the serum and lens of senile cataract patients].

作者信息

Chen C Z

机构信息

Beijing Institute of Ophthalmology.

出版信息

Zhonghua Yan Ke Za Zhi. 1992 Nov;28(6):355-7.

PMID:1306472
Abstract

The contents of Fe, Al, Cu, Zn, Ca, Mg and P in the serum and lens of senile cataract patients were determined with inductively coupled plasma (ICP) spectrometry to find that (1) the Fe, Al, Zn and Ca levels in senile cataractous lenses were significantly higher, and the P level lower than those in normal subjects; however, the serum levels of Fe, Al, Zn and Ca were significantly lower, and the level of P higher than those in normal subjects; (2) the serum levels of Cu and Zn varied with the duration of cataract, which could explain the inconsistency among authors with regard to these parameters; (3) the relation between Fe and Al and the development of cataract remained to be elucidated; (4) the Ca/P ratio in senile cataractous lenses was 50 times (1:0.02) that in clear lenses; these 2 elements were regarded to have close relation with cataractogenesis; and (5) Cu and Mg were not related to cataractogenesis, a finding in agreement with most reports.

摘要

采用电感耦合等离子体(ICP)光谱法测定老年白内障患者血清和晶状体中Fe、Al、Cu、Zn、Ca、Mg和P的含量,结果发现:(1)老年白内障晶状体中Fe、Al、Zn和Ca的含量显著高于正常受试者,而P的含量低于正常受试者;然而,血清中Fe、Al、Zn和Ca的含量显著低于正常受试者,而P的含量高于正常受试者;(2)血清中Cu和Zn的含量随白内障病程而变化,这可以解释不同作者在这些参数上的不一致;(3)Fe和Al与白内障发生发展的关系尚待阐明;(4)老年白内障晶状体中Ca/P比值是透明晶状体的50倍(1:0.02);这两种元素被认为与白内障发生密切相关;(5)Cu和Mg与白内障发生无关,这一发现与大多数报道一致。

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