Blanche P, Sicard D
Département de Médecine Interne, Hôpital Cochin, Paris.
Rev Rhum Mal Osteoartic. 1992 Nov 30;59(11):755-6.
A female patient from the French Antilles developed renal failure due to pure chronic interstitial nephritis six months after the onset of systemic lupus erythematosus (SLE) for which she was taking hydroxychloroquine. Over time, results of biologic tests became suggestive of concomitant Gougerot-Sjögren syndrome, but neither the clinical nor the histologic findings were consistent with this diagnosis. The diagnosis of overlap syndrome between SLE and Gougerot-Sjögren syndrome was established only six years later when the patient developed ocular and oral sicca syndrome with enlargement of the parotid glands.
一名来自法属安的列斯群岛的女性患者，在系统性红斑狼疮（SLE）发病6个月后因单纯慢性间质性肾炎出现肾衰竭，当时她正在服用羟氯喹。随着时间推移，生物学检查结果提示合并有古热罗-舍格伦综合征，但临床和组织学检查结果均与该诊断不符。直到6年后患者出现眼干、口干综合征以及腮腺肿大时，才确诊为SLE与古热罗-舍格伦综合征重叠综合征。
