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[不同体重大鼠肝脏中烟碱酸7 - 14C生物分解的统计分析]

[Statistical analysis of biological breakdown of nicotinic acid 7-14C in rat liver of various weight].

作者信息

Vovnianko E K, Diul'din O A

出版信息

Ukr Biokhim Zh. 1976 Jan-Feb;48(1):122-7.

PMID:130703
Abstract

Statistical methods are considered for eliminating the errors caused by the individual fluctuations of the animals organs weight, different ratio of organs weight to the weight statistical processing the data on the dynamics of labelled nicotinic acid evacuation and determination of the acid half-life in the rat liver. The mean liver weight was estimated by means of Huxley's allometry formula. Dynamics of NA was approximated by using the formula kappa=ate-betat in the computer "MHP-2" and the least squares method.

摘要

考虑采用统计方法来消除动物器官重量个体波动、器官重量与体重不同比例所导致的误差,对标记烟酸排泄动态数据进行统计处理,并测定大鼠肝脏中该酸的半衰期。通过赫胥黎的异速生长公式估算肝脏平均重量。在计算机“MHP - 2”上利用公式kappa = ate - betat和最小二乘法对烟酰胺(NA)的动态进行近似处理。

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