Zhang M H, Yang H Z
Department of Ophthalmology, Ruijin Hospital, Shanghai Second Medical University.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1992;10(3):215-8.
Retinochoroiditis is a frequent ocular lesion in toxoplasmosis. It may be severe, and even lead to blindness. Sixteen cases of toxoplasmic retinochoroiditis verified through IFA were presented in this paper. Among these cases, 1 was of the multifocal type, its appearance being similar to that of the Coats disease; while the other 15 were of the focal type resembling to the central exudative retinitis (Rieger disease) or retinochoroidal scar. Serological finding of all the cases showed a positive IFA titer of > 1:80. A combination of pyrimethamine and sulfadiazine as well as spiramycin in addition to dexamethasone had been administered and proved effective. Since toxoplasmosis mostly occurs as latent and examination of the eye cannot differentiate from other causes of retinochoroiditis, so such clinical report of toxoplasmic retinochoroiditis was rare with particular reference in our country. The authors claimed that any individual presenting with retinochoroiditis suspected of toxoplasmosis should be subjected to serologic antibody test for establishing diagnosis.
视网膜脉络膜炎是弓形虫病常见的眼部病变。病情可能较为严重,甚至会导致失明。本文报告了16例经间接荧光抗体法(IFA)确诊的弓形虫性视网膜脉络膜炎病例。其中,1例为多灶型,其表现与柯茨病相似;另外15例为病灶型,类似中心性渗出性视网膜病变(里格尔病)或视网膜脉络膜瘢痕。所有病例的血清学检查结果显示,间接荧光抗体效价>1:80呈阳性。已给予乙胺嘧啶、磺胺嘧啶联合螺旋霉素以及地塞米松治疗,且证明有效。由于弓形虫病大多呈潜伏状态,眼部检查无法与其他视网膜脉络膜炎病因相鉴别,因此在我国,这种弓形虫性视网膜脉络膜炎的临床报告较为罕见。作者称,任何疑似弓形虫病的视网膜脉络膜炎患者都应接受血清学抗体检测以明确诊断。