Kovác A, Boldizsar J, Földes O, Pavlovic M
Postgraduate Medical School in Bratislava, Czech.
Mater Med Pol. 1992 Oct-Dec;24(4):241-2.
The prostaglandins 6-keto Pgf1 alpha,PG F2 alpha and thromboxane B2 before and during haemodialysis were studied by means of radioisotope method. A significant increase of 6-keto PGF1 alpha and decrease of PGF2 alpha was found. The concentration of thromboxane B2 was markedly, but not significantly decreased. This constellation inhibiting the thrombocytes aggregation and promoting vasodilation seems to be favourable as far as biocompatibility is concerned. Dialysis treatment caused no significant changes in prostaglandins concentration.
采用放射性同位素法对血液透析前及透析过程中的前列腺素6-酮前列环素F1α、前列腺素F2α和血栓素B2进行了研究。发现6-酮前列环素F1α显著增加，前列腺素F2α降低。血栓素B2的浓度显著降低，但不明显。就生物相容性而言，这种抑制血小板聚集和促进血管舒张的组合似乎是有利的。透析治疗对前列腺素浓度无显著影响。
