Tian L
Third Affiliated Hospital, Norman Bethune University of Medical Sciences, Changchun.
Zhonghua Wai Ke Za Zhi. 1990 Jun;28(6):339-41, 381.
Platelet aggregation rate (PAR), plasma concentration of TXB2 and 6-Keto-PGF1 alpha were measured in 26 patients with shock (hypovolumic shock 10 and septic shock 16) and 10 controls. PAR, plasma TXB2 and 6-Keto-PGF1 alpha were increased during shock, with TXB2 increased more significantly than 6-Keto-PGF1 alpha, accordingly the TXB2/6-Keto-PGF1 alpha ratio were raised during shock, especially in the septic cases. PAR, plasma TXB2 and 6-Keto-PGF1 alpha will decrease while shock become subsiding, and elevate while shock become irreversible. As a rule, the change of PAR is parallel with the concentration of plasma TXB2. The speed of platelet aggregation and plasma TXB2 concentration were higher in eleven mortal cases.
对26例休克患者（10例低血容量性休克和16例脓毒性休克）及10例对照者测定血小板聚集率（PAR）、血浆TXB2和6 - 酮 - PGF1α浓度。休克期间PAR、血浆TXB2和6 - 酮 - PGF1α升高，其中TXB2升高比6 - 酮 - PGF1α更显著，因此休克期间TXB2/6 - 酮 - PGF1α比值升高，尤其是脓毒症病例。休克缓解时PAR、血浆TXB2和6 - 酮 - PGF1α会降低，休克不可逆时则升高。通常，PAR的变化与血浆TXB2浓度平行。11例死亡病例的血小板聚集速度和血浆TXB2浓度更高。
