Biocompatibility and biofunctionality of implanted materials.

The mechanical and chemical properties of metals, such as titanium, titanium-based alloys and cobalt-based alloys, and ceramics, such as Bioglass and calcium phosphate, make them suitable for implant applications. However, several factors affect the biologic response to these implanted materials. The predominant tissue found at the implant interface is affected by implant stability, material biocompatibility, and implant design and implant placement into the surgical site. Improvements in implant design and surface preparation may improve implant longevity and fixation for all implants materials.