de Jong E, Peterse J L, van Dongen J A
Department of Surgery, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam.
Eur J Surg Oncol. 1992 Feb;18(1):64-6.
Three patients are described having locally recurrent invasive breast cancer after breast ablation for ductal carcinoma in situ (DCIS). All had initially extensive type ductal carcinoma in situ without evidence of invasion in adequately sampled microscopical studies. One patient developed a scar recurrence and lung metastases 2 years after surgery; one patient showed a scar recurrence 3 years after operation and one patient had a recurrence in the chest wall 27 years after surgery. Although generally stated that ablative therapy offers a 100% cure in case of DCIS, these cases illustrate that local recurrence may occur. Possible causes and preventions are discussed.
本文描述了3例在因原位导管癌（DCIS）进行乳房切除术后出现局部复发性浸润性乳腺癌的患者。所有患者最初均为广泛型原位导管癌，在充分取材的显微镜检查中均无浸润证据。1例患者在术后2年出现瘢痕复发和肺转移；1例患者在术后3年出现瘢痕复发，1例患者在术后27年出现胸壁复发。尽管一般认为消融治疗可使DCIS患者获得100%的治愈，但这些病例表明仍可能发生局部复发。文中讨论了可能的原因及预防措施。
