Holdorff B, Sinn M, Häring R, Simon R S, Bradac G B
Rofo. 1976 Mar;124(3):259-64. doi: 10.1055/s-0029-1230326.
Amongst late radiation damage, lesions of the cerebral arteries are relatively rare. The relationship between the radiation and arterio-sclerosis is discussed in connection with a 63-year old female patient with an atheromatous carotid stenosis; at the age of 5 years she received high dose rate radiation for cervical node tuberculosis. From animal experiments and an increasing number of human observations, it is concluded that radiation may be a predisposing and accelerating local factor in the formation of arterio-sclerosis. Amongst the recognised cases of radiogenic carotid stenosis or occlusion, the latent period averages 30 (9-57) years.
在晚期辐射损伤中,脑动脉病变相对少见。结合一名患有动脉粥样硬化性颈动脉狭窄的63岁女性患者,讨论了辐射与动脉硬化之间的关系;她5岁时因颈部淋巴结结核接受了高剂量率放疗。从动物实验和越来越多的人体观察结果来看,得出的结论是辐射可能是动脉硬化形成的一个诱发和加速局部因素。在已确认的放射性颈动脉狭窄或闭塞病例中,潜伏期平均为30(9 - 57)年。