Eskenasy A
Morphol Embryol (Bucur). 1975;21(4):289-98.
Some relationships between the lung reacting cell populations connected to the air and blood ways are investigated by elicitation with proteins in Freund's adjuvant and with SiO2. The agents were intratracheally and respectively intravenously injected into rabbits concomitantly or in different orders and times. The developmental analysis of the alveolar silicotic nodules and of the proteolipidic perivascular ones pointed out the involvement of both reacting cell systems in relation with the administration route, the involvement of local cells only, when the agent is less active and the arrival of blood mononuclears when the agent is more active. A concurrent taking part of the reacting cell systems in the process is demonstrated. The immune phenomena developed by both the used agents also elimine numerous cells from the formation process of nodules, and allow the production of hypersensitive reactions of the immediate and cellular type which influence the integrity and cellularity of formed nodules. The relationships between these two reacting cell systems of the lung appear to be not only quantitative but also qualitative.
通过用弗氏佐剂中的蛋白质和二氧化硅进行激发，研究了与气道和血液途径相连的肺反应细胞群体之间的一些关系。将这些试剂经气管内和分别经静脉内同时或以不同顺序和时间注射到兔子体内。肺泡硅结节和蛋白脂质血管周围结节的发育分析指出，两种反应细胞系统与给药途径有关，当试剂活性较低时仅涉及局部细胞，而当试剂活性较高时血液单核细胞会到达。证明了反应细胞系统在该过程中同时参与。两种所用试剂引发的免疫现象还从结节形成过程中清除了大量细胞，并允许产生即刻型和细胞型超敏反应，这影响了形成结节的完整性和细胞性。肺的这两种反应细胞系统之间的关系似乎不仅是数量上的，而且是质量上的。
