日本采用脑室内注射利巴韦林治疗亚急性硬化性全脑炎的试验。
Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan.
作者信息
Tomoda Akemi, Nomura Keiko, Shiraishi Seiji, Hamada Akinobu, Ohmura Takafumi, Hosoya Mitsuaki, Miike Teruhisa, Sawaishi Yukio, Kimura Hiroshi, Takashima Hiroshi, Tohda Yoshihiro, Mori Kenji, Kato Zenichiro, Fukushima Ai, Nishio Hisanori, Nezu Akio, Nihei Kenji
机构信息
Department of Child Development, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto 860-0811, Japan.
出版信息
Brain Dev. 2003 Oct;25(7):514-7. doi: 10.1016/s0387-7604(03)00062-7.
Ten patients with SSPE were surveyed during the last 4 years from the viewpoint of clinical safety for use of ribavirin therapy. Although effectiveness varied among cases, they were all treated safely with intraventricular ribavirin. This study suggests that treatment is safe and well-tolerated.
在过去4年里，我们从临床安全性的角度对10例亚急性硬化性全脑炎（SSPE）患者使用利巴韦林治疗的情况进行了调查。尽管不同病例的疗效有所差异，但所有患者经脑室内注射利巴韦林治疗均安全。本研究表明该治疗方法安全且耐受性良好。
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