Weigler B J
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis.
Clin Infect Dis. 1992 Feb;14(2):555-67. doi: 10.1093/clinids/14.2.555.
B virus is a zoonotic alpha-herpesvirus enzootic in Asian monkeys of the genus Macaca. At least 25 cases of human disease caused by B virus have occurred to date, leading to death in 16 instances. Advances in the technology available for the diagnosis of B virus infection and in the agents for its treatment are improving the prognosis for cases in human beings. Efforts are under way at several institutions in the United States to establish B virus-free colonies of rhesus macaques for use in biomedical research. Unfortunately, the epidemiology of B virus in group-housed macaques is poorly understood. The elucidation of factors important in the transmission of B virus between monkeys will greatly enhance efforts to eradicate this virus and may help to minimize further human exposure to the agent.
B病毒是一种人畜共患的甲型疱疹病毒，在猕猴属的亚洲猴中呈地方流行性。迄今为止，至少已发生25例由B病毒引起的人类疾病，其中16例导致死亡。用于诊断B病毒感染的技术以及治疗药物方面的进展正在改善人类病例的预后。美国几家机构正在努力建立无B病毒的恒河猴群体，用于生物医学研究。不幸的是，人们对群居猕猴中B病毒的流行病学了解甚少。阐明对B病毒在猴子之间传播至关重要的因素，将极大地推动根除这种病毒的工作，并可能有助于尽量减少人类进一步接触该病原体的机会。
