Wilfong A A, Parke J T, McCrary J A
Department of Pediatric Neurology, Baylor College of Medicine, Texas Children's Hospital, Houston 77030.
Pediatr Neurol. 1992 Jan-Feb;8(1):77-9. doi: 10.1016/0887-8994(92)90060-c.
The association between Beckwith-Wiedemann syndrome and hepatoblastoma is well established and relatively commonplace. The occurrence of opsoclonus-myoclonus syndrome in individuals with occult neoplasia is also well documented. However, the development of opsoclonus-myoclonus syndrome in an infant with Beckwith-Wiedemann syndrome and hepatoblastoma has not been reported previously. The list of underlying causes of opsoclonus-myoclonus syndrome should be expanded to include hepatoblastoma, particularly in any child with features suggestive of Beckwith-Wiedemann syndrome.
贝克威思-维德曼综合征与肝母细胞瘤之间的关联已得到充分证实且较为常见。隐匿性肿瘤患者出现眼阵挛-肌阵挛综合征的情况也有充分记录。然而，此前尚未报道过患有贝克威思-维德曼综合征和肝母细胞瘤的婴儿发生眼阵挛-肌阵挛综合征。眼阵挛-肌阵挛综合征的潜在病因清单应予以扩充，以纳入肝母细胞瘤，特别是在任何具有提示贝克威思-维德曼综合征特征的儿童中。
