Hömberg V, Reiners K, Toyka K V
Department of Neurology, Heinrich-Heine-University of Düsseldorf, Germany.
Muscle Nerve. 1992 Apr;15(4):467-70. doi: 10.1002/mus.880150409.
Conduction block [a significant reduction in compound muscle action potential (CMAP) amplitude after proximal compared to distal stimulation] is often found in demyelinating neuropathies, including inflammatory neuropathies and degenerative neuropathies, such as "liability to pressure neuropathy." There is experimental evidence that a transient conduction block can occur in rats after ischemic lesions of peripheral nerves are induced either by ligation of arterial vessels supplying nerve trunks, or by injection of arachidonic acid into peripheral arterial vessels. Conduction block has also recently been described in cases with necrotizing vasculitis. To date, however, no example of a reversible conduction block has been reported in human ischemic neuropathy.
传导阻滞（与远端刺激相比，近端刺激后复合肌肉动作电位（CMAP）幅度显著降低）常见于脱髓鞘性神经病，包括炎性神经病和退行性神经病，如“压力性神经病易感性”。有实验证据表明，通过结扎供应神经干的动脉血管或向周围动脉血管注射花生四烯酸诱导大鼠周围神经缺血性损伤后，可出现短暂性传导阻滞。最近在坏死性血管炎病例中也描述了传导阻滞。然而，迄今为止，人类缺血性神经病中尚未报道可逆性传导阻滞的病例。
