Sawyer J R, Tryka A F, Lewis J M
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock.
Am J Surg Pathol. 1992 Apr;16(4):411-6. doi: 10.1097/00000478-199204000-00010.
We report an intraabdominal desmoplastic small round-cell tumor that contains a novel reciprocal chromosome translocation t(11;22)(p13;q12). The tumor showed a reciprocal chromosome translocation which is different from the (11;22)(q24;q12) translocations seen in Ewing's and other small-cell tumors but affects the same break-point on chromosome 22(q12). This reciprocal chromosome translocation may prove to be a marker for intraabdominal desmoplastic small round-cell tumors.
我们报告了一例腹腔内促结缔组织增生性小圆细胞肿瘤，其含有一种新的相互易位染色体t(11;22)(p13;q12)。该肿瘤显示出一种相互易位染色体，它不同于尤因肉瘤及其他小细胞肿瘤中所见的(11;22)(q24;q12)易位，但影响22号染色体上相同的断点(q12)。这种相互易位染色体可能被证明是腹腔内促结缔组织增生性小圆细胞肿瘤的一个标志物。
