Washio M, Iseki K, Onoyama K, Oh Y, Nakamoto M, Fujimi S, Fujishima M
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City, Japan.
Nephrol Dial Transplant. 1992;7(2):121-4. doi: 10.1093/oxfordjournals.ndt.a092080.
After successful subtotal parathyroidectomy (PTX) in 10 chronic haemodialysis patients, significant elevation of Epo was observed, from 48.4 +/- 17.8 mU/ml(M +/- SEM) at preoperative state to 103.3 +/- 34.7 mU/ml at 6 h and 163.4 +/- 50.2 mU/ml at 12 h after PTX. Significant reductions in both PTH-m and ionized calcium (iCa) were confirmed. Since Epo did not increase in the cases with an inadequate PTX and ovariectomy, an abrupt reduction in PTH with a decrease in iCa may play some role in the elevation of Epo.
在10例慢性血液透析患者成功进行甲状旁腺次全切除术后，观察到促红细胞生成素（Epo）显著升高，从术前的48.4±17.8 mU/ml（平均值±标准误）升至术后6小时的103.3±34.7 mU/ml以及术后12小时的163.4±50.2 mU/ml。同时证实甲状旁腺激素（PTH-m）和离子钙（iCa）均显著降低。由于在甲状旁腺切除不充分及卵巢切除的病例中Epo未升高，PTH的突然降低及iCa的下降可能在Epo升高过程中起了一定作用。
