慢性血液透析患者甲状旁腺次全切除术后血清促红细胞生成素水平升高。
Elevation of serum erythropoietin after subtotal parathyroidectomy in chronic haemodialysis patients.
作者信息
Washio M, Iseki K, Onoyama K, Oh Y, Nakamoto M, Fujimi S, Fujishima M
机构信息
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City, Japan.
出版信息
Nephrol Dial Transplant. 1992;7(2):121-4. doi: 10.1093/oxfordjournals.ndt.a092080.
After successful subtotal parathyroidectomy (PTX) in 10 chronic haemodialysis patients, significant elevation of Epo was observed, from 48.4 +/- 17.8 mU/ml(M +/- SEM) at preoperative state to 103.3 +/- 34.7 mU/ml at 6 h and 163.4 +/- 50.2 mU/ml at 12 h after PTX. Significant reductions in both PTH-m and ionized calcium (iCa) were confirmed. Since Epo did not increase in the cases with an inadequate PTX and ovariectomy, an abrupt reduction in PTH with a decrease in iCa may play some role in the elevation of Epo.
在10例慢性血液透析患者成功进行甲状旁腺次全切除术后，观察到促红细胞生成素（Epo）显著升高，从术前的48.4±17.8 mU/ml（平均值±标准误）升至术后6小时的103.3±34.7 mU/ml以及术后12小时的163.4±50.2 mU/ml。同时证实甲状旁腺激素（PTH-m）和离子钙（iCa）均显著降低。由于在甲状旁腺切除不充分及卵巢切除的病例中Epo未升高，PTH的突然降低及iCa的下降可能在Epo升高过程中起了一定作用。
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