al-Jurayyan N A, al Ayed I H, al-Nasser M N, al-Mugeiren M M, Boohene A G, al Herbish A S
Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
J Trop Pediatr. 1992 Feb;38(1):12-6. doi: 10.1093/tropej/38.1.12.
The epidemiology, clinicopathological features, and response to therapy of 63 Saudi patients with visceral leishmaniasis are described. The clinical features in our cases were similar to those described from Asir province, India, and Ethiopia, except for the presence of lymphadenopathy. Fever, hepatosplenomegaly, pancytopenia, and liver dysfunction were common findings. The unusual feature is the seasonal variation in the distribution of the disease. The response to sodium stibogluconate was excellent and the mortality rate was low (less than 1 per cent).
本文描述了63例沙特内脏利什曼病患者的流行病学、临床病理特征及治疗反应。我们病例的临床特征与印度阿西尔省和埃塞俄比亚所描述的相似,但存在淋巴结病。发热、肝脾肿大、全血细胞减少和肝功能障碍是常见表现。该病分布的季节性变化是其不寻常的特征。对葡萄糖酸锑钠的反应良好,死亡率较低(低于1%)。