Das D K, Mohil R S, Kashyap V, Khan I U, Mandal A K, Gulati S M
Division of Cytology, Maulana Azad Medical College Campus, New Delhi, India.
Acta Cytol. 1992 May-Jun;36(3):399-403.
A 30-year-old woman presented with a lump in the left breast and left axillary lymphadenopathy that, on fine needle aspiration cytology (FNAC), proved to be duct cell carcinoma with metastasis. Histology of the radical mastectomy specimen showed a mixed colloid carcinoma. Axillary lymph nodes revealed a variety of pathologic changes consisting of reactive hyperplasia, tuberculosis and metastasis. A combination of a tuberculous lesion and metastasis in the same lymph nodes was also found. During follow-up, after radiotherapy, the patient developed left supraclavicular and right cervical lymphadenopathy that, on FNAC, revealed a tuberculous lesion and metastasis, respectively. The rarity of this condition with double pathology is highlighted, and the reason behind the limitations of FNA in subtyping the primary malignancy and its failure to detect the tuberculous lesion in the axillary lymph node are discussed.
一名30岁女性因左乳肿块及左腋窝淋巴结肿大就诊,细针穿刺细胞学检查(FNAC)证实为导管细胞癌伴转移。根治性乳房切除术标本的组织学检查显示为混合性胶样癌。腋窝淋巴结显示出多种病理变化,包括反应性增生、结核和转移。在同一淋巴结中还发现了结核病变与转移并存的情况。随访期间,放疗后患者出现左锁骨上和右颈部淋巴结肿大,FNAC检查分别显示为结核病变和转移。强调了这种具有双重病理情况的罕见性,并讨论了FNA在原发性恶性肿瘤亚型分类方面的局限性及其未能检测出腋窝淋巴结结核病变的原因。