Pujani Mukta, Khan Sabina, Hassan Mohd Jaseem, Jetley Sujata, Raina Prabhat Kumar
Breast Dis. 2015;35(3):195-8. doi: 10.3233/BD-150405.
Concomitant breast cancer metastasis and tubercular lymphadenitis in axillary lymph node is an extremely rare occurrence. Axillary lymph node metastasis is the most important factor in the staging of breast carcinoma and the number of axillary nodes showing metastases alters the stage. As tuberculosis also produces nodal enlargement, this can mimic or complicate the staging of malignant disease. Dual pathology in an organ can lead to difficulties in interpretation and inappropriate treatment of tuberculosis as well as carcinoma breast. Moreover, fine needle aspiration cytology (FNAC) from such cases may be misleading if only one of the diseases is picked up. Therefore, the need for multiple attempts at FNAC should be stressed upon for all palpable lumps. We report a case of infiltrating duct carcinoma breast in a 45-year-old female where tuberculosis was discovered in axillary lymph nodes in addition to metastases. As the present case led to incidental discovery of tuberculosis with tumor metastasis, it reinforces the possibility of a coexistent lesion in the pathologists' mind, especially in regions endemic for tuberculosis.
乳腺癌腋窝淋巴结转移与结核性淋巴结炎同时发生极为罕见。腋窝淋巴结转移是乳腺癌分期的最重要因素,出现转移的腋窝淋巴结数量会改变分期。由于结核病也会导致淋巴结肿大,这可能会模拟恶性疾病的分期或使其复杂化。一个器官出现双重病理情况会导致对结核病和乳腺癌的解读困难以及不恰当的治疗。此外,如果仅检出其中一种疾病,此类病例的细针穿刺抽吸细胞学检查(FNAC)可能会产生误导。因此,对于所有可触及的肿块,应强调多次进行FNAC检查的必要性。我们报告一例45岁女性浸润性导管癌病例,其腋窝淋巴结除转移外还发现了结核。由于本病例偶然发现了伴有肿瘤转移的结核病,这强化了病理学家脑海中存在共存病变的可能性,尤其是在结核病流行地区。