KELLNER A, ROBERTSON T
J Exp Med. 1954 May 1;99(5):495-503. doi: 10.1084/jem.99.5.495.
Focal myocardial necrosis that was often extensive was found in a high percentage of rabbits, guinea pigs, and mice given a single intravenous injection of crystalline streptococcal proteinase. The findings are discussed in relation to their possible implications for the pathogenesis of the cardiac lesions of rheumatic fever.
在单次静脉注射结晶链球菌蛋白酶的兔、豚鼠和小鼠中,发现有高比例的动物出现了常为广泛性的局灶性心肌坏死。本文结合这些发现对其可能与风湿热心脏病变发病机制的关联进行了讨论。