Hata T, Deter R L, Aoki S, Makihara K, Hata K, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
J Clin Ultrasound. 1992 Jun;20(5):321-7. doi: 10.1002/jcu.1870200504.
Growth of the fetal spleen has been monitored by measurements of the maximal length (SL), profile circumference (SC), and profile area (SA) of the spleen, from 20 weeks to 41 weeks, menstrual age. Growth curves for these parameters have been determined using a specially developed growth curve model [P = c(t)k + s (t)]. R2 values of 94.3%, 94.9%, and 96.3% were obtained for SL, SC, and SA, respectively. Variability analysis indicated some progressive increase in variability with menstrual age for these three parameters. Variability data were used with the growth curve models to determine standard curves for SL, SC, and SA. These standard curves provide a superior means for evaluating the normal splenic growth in the fetus and for identifying splenic abnormalities in utero.
通过测量脾脏的最大长度（SL）、轮廓周长（SC）和轮廓面积（SA），对月经龄20周～41周胎儿脾脏的生长情况进行了监测。使用专门开发的生长曲线模型[P = c(t)k + s (t)]确定了这些参数的生长曲线。SL、SC和SA的R2值分别为94.3%、94.9%和96.3%。变异性分析表明，这三个参数的变异性随月经龄有所增加。将变异性数据与生长曲线模型结合，确定了SL、SC和SA的标准曲线。这些标准曲线为评估胎儿脾脏的正常生长及识别子宫内脾脏异常提供了更好的方法。
