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胎儿生长的数学建模:个体生长曲线标准的制定。

Mathematic modeling of fetal growth: development of individual growth curve standards.

作者信息

Deter R L, Rossavik I K, Harrist R B, Hadlock F P

出版信息

Obstet Gynecol. 1986 Aug;68(2):156-61.

PMID:3526216
Abstract

To provide a more precise means for monitoring individual fetal growth and to improve the detection of growth abnormalities, the Rossavik growth model [P = c(t)k + s(t)] has been used to establish individual growth curve standards. A longitudinal study of the growth of one-dimensional (biparietal diameter, head, and abdominal circumferences), two-dimensional (head and abdominal profile areas), and three-dimensional (head and abdominal volumes) parameters in 18 normal fetuses has revealed that the growth of all parameters can be well-described by the Rossavik model (R2: 97.2 to 99.5%). Strong statistical evidence was obtained indicating that the coefficient k is principally a geometric coefficient having a value determined primarily by the dimension of the parameter being studied. It was also found that the coefficients c and s can be estimated from the data obtained before 28 weeks' conceptual age. Individual growth curve models derived from data obtained before 28 weeks were capable of predicting growth beyond 28 weeks. These models provide growth curve standards for evaluating individual fetal growth beyond 28 weeks.

摘要

为了提供一种更精确的方法来监测个体胎儿的生长情况,并提高对生长异常的检测能力,罗萨维克生长模型[P = c(t)k + s(t)]已被用于建立个体生长曲线标准。一项对18例正常胎儿的一维(双顶径、头围和腹围)、二维(头部和腹部轮廓面积)和三维(头部和腹部体积)参数生长情况的纵向研究表明,罗萨维克模型能够很好地描述所有参数的生长情况(R²:97.2%至99.5%)。获得了强有力的统计证据,表明系数k主要是一个几何系数,其值主要由所研究参数的维度决定。还发现,系数c和s可以根据妊娠28周前获得的数据进行估计。从妊娠28周前获得的数据得出的个体生长曲线模型能够预测28周后的生长情况。这些模型为评估28周后的个体胎儿生长提供了生长曲线标准。

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Mathematic modeling of fetal growth: development of individual growth curve standards.胎儿生长的数学建模:个体生长曲线标准的制定。
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