Imbs J L, Schmidt M, Belhadj-Mostefa H, Schwartz J
C R Seances Soc Biol Fil. 1975;169(5):1365-70.
The effects of propranolol (l mg/kg/H infused in the renal artery) on the diuretic action of furosemide (20 mg/kg i.v.) have been studied in pentobarbital anesthetized dogs. We obtained the 3 following results : the urine remained isotonic to the plasma during the 6 hours following the furosemide injection ; the urinary output of sodium and water, measured during 6 hours after furosemide injection, was increased ; the renin hypersecretion was inhibited.
在戊巴比妥麻醉的犬身上,研究了普萘洛尔(以1毫克/千克/小时的速度注入肾动脉)对呋塞米(20毫克/千克静脉注射)利尿作用的影响。我们得到了以下3个结果:在注射呋塞米后的6小时内,尿液与血浆保持等渗;在注射呋塞米后6小时内测量的钠和水的尿量增加;肾素分泌过多受到抑制。