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Levodopa in Huntingtons chorea.

作者信息

Sishta S K, Templer D I

出版信息

Can Med Assoc J. 1976 May 8;114(9):798-9.

Abstract

Sixteen patients with Huntington's chorea were treated for periods as long as 8 months with levodopa. The condition of none of the patients improved; in fact, there appeared to be an exacerbation of chorea and dementia in addition to undesirable behavioural changes. Therefore, future use of levodopa in these patients is not warranted. The postulated association of low homovanillic acid values in cerebrospinal fluid and favourable response to levodopa therapy was not borne out.

摘要

引用本文的文献

1
Levodopa-Responsive Chorea: A Review.
Ann Indian Acad Neurol. 2020 Mar-Apr;23(2):211-214. doi: 10.4103/aian.AIAN_221_19. Epub 2020 Feb 25.

本文引用的文献

1
Amine metabolism in the human brain: further evaluation of the probenecid test.
Brain Res. 1971 Dec 10;35(1):221-30. doi: 10.1016/0006-8993(71)90607-x.
2
Huntington's chorea: an electroencephalographic and psychometric study.
Electroencephalogr Clin Neurophysiol. 1974 Apr;36(4):387-93. doi: 10.1016/0013-4694(74)90188-6.
3
Levodopa in Huntington's chorea.
Lancet. 1972 Apr 22;1(7756):903. doi: 10.1016/s0140-6736(72)90773-8.

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