Nakao N, Kamino K, Miura K, Takayasu Y, Ohnishi M, Miura T
Department of Radiology, Hyogo College of Medicine, Japan.
Radiat Med. 1992 Jan-Feb;10(1):13-8.
Transcatheter arterial embolization (TAE) was performed in 1,058 cases of hepatocellular carcinoma (HCC), and the prognosis after TAE in HCC was then assessed from the long-term follow-up data. The results indicated that the prognosis was better for small tumors, and was significantly better for capsulated than noncapsulated tumors. For this reason, the prognosis of small tumors was not always better than that of large tumors. The prognosis worsened as the severity of portal obstruction increased. The prognosis improved with the use of Lipiodol (iodized oil). It was found that the use of anticancer drugs in combination with TAE, however, did not significantly affect the prognosis as compared with TAE alone. The 1-, 2-, 3-, 4-, and 5-year overall survival rates were 70%, 51%, 29%, 14%, and 5%, respectively.
对1058例肝细胞癌(HCC)患者实施了经导管动脉栓塞术(TAE),然后根据长期随访数据评估HCC患者TAE术后的预后。结果表明,小肿瘤患者的预后较好,有包膜的肿瘤患者的预后明显优于无包膜的肿瘤患者。因此,小肿瘤患者的预后并不总是优于大肿瘤患者。随着门静脉阻塞严重程度的增加,预后恶化。使用碘油后预后有所改善。然而,发现与单纯TAE相比,联合使用抗癌药物与TAE对预后没有显著影响。1年、2年、3年、4年和5年的总生存率分别为70%、51%、29%、14%和5%。