Williams E D
Regional Medical Physics Department, District General Hospital, Sunderland, UK.
Semin Nucl Med. 1992 Apr;22(2):112-21. doi: 10.1016/s0001-2998(05)80086-8.
Although single photon emission computed tomography (SPECT) imaging has established a place for itself in clinical nuclear medicine for heart and brain studies, its place in renal imaging is not yet clear. Renal SPECT has been subject to limitations imposed by the efficiency of imaging equipment, and has been confined to use with static imaging agents such as technetium-99m (99mTc) dimercaptosuccinate (DMSA). SPECT has been used to investigate space-occupying lesions and anatomical abnormalities, and for quantitative studies of renal uptake and volume. In these areas, it has provided little advantage over conventional imaging, but it has been helpful in individual cases. High-resolution SPECT is a promising new development, which may have applications in detecting and classifying renal scarring. It deserves careful evaluation.
尽管单光子发射计算机断层扫描（SPECT）成像在临床核医学的心脏和脑部研究中已占据一席之地，但其在肾脏成像中的地位尚不明晰。肾脏SPECT受到成像设备效率的限制，并且一直局限于与锝-99m（99mTc）二巯基丁二酸（DMSA）等静态成像剂配合使用。SPECT已被用于研究占位性病变和解剖学异常，以及肾脏摄取和体积的定量研究。在这些领域，它相较于传统成像几乎没有优势，但在个别病例中有所帮助。高分辨率SPECT是一项有前景的新进展，可能在检测和分类肾脏瘢痕方面有应用价值。它值得仔细评估。
