Birdsall S H, MacLennan K A, Gusterson B A
Section of Cell and Experimental Pathology, Institute of Cancer Research, Sutton, Surrey, England.
Cancer Genet Cytogenet. 1992 May;60(1):74-7. doi: 10.1016/0165-4608(92)90236-2.
Cytogenetic analysis of short-term cultures from a phyllodes tumor showed clonal chromosome changes including t(6;12)(q23;q13) and t(10;16)(q22;p11). This is the first reported karyotype in this tumor type. We discuss the breakpoints of these translocations in relation to the involvement of possible candidate genes.