Chiprut R O, Viteri A, Jamroz C, Dyck W P
Gastroenterology. 1976 Jun;70(6):1141-3.
The occurrence of cholestatic jaundice in a patient receiving griseofulvin is described. The clinical manifestations, laboratory features, and pathological lesion of drug-induced hepatotoxicity are discussed. Complete recovery followed the discontinuation of drug administration. The potential hepatotoxicity of griseofulvin and the importance of close monitoring of liver function studies in patients receiving this drug are emphasized.
本文描述了一名接受灰黄霉素治疗的患者发生胆汁淤积性黄疸的情况。讨论了药物性肝毒性的临床表现、实验室特征及病理损害。停药后患者完全康复。强调了灰黄霉素潜在的肝毒性以及对接受该药治疗的患者密切监测肝功能检查的重要性。
