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病例报告:与赖诺普利治疗相关的严重症状性低钠血症

Case report: severe symptomatic hyponatremia associated with lisinopril therapy.

作者信息

Subramanian D, Ayus J C

机构信息

Department of Medicine, Baylor College of Medicine, Houston, Texas.

出版信息

Am J Med Sci. 1992 Mar;303(3):177-9. doi: 10.1097/00000441-199203000-00009.

Abstract

A 63-year-old white female who was being treated for hypertension with lisinopril presented with seizures, altered mental status, and a serum sodium of 101 mEq/L. Serum sodium prior to initiation of lisinopril therapy was 137 mEq/L. The hyponatremia was corrected and did not recur after lisinopril was stopped. The hyponatremia may have been a result of polydipsia and inappropriate antidiuresis secondary to ACE-inhibitor therapy.

摘要

一名63岁的白人女性,正在接受赖诺普利治疗高血压,出现癫痫发作、精神状态改变,血清钠为101 mEq/L。开始使用赖诺普利治疗前血清钠为137 mEq/L。低钠血症得到纠正,停用赖诺普利后未复发。低钠血症可能是由于多饮和继发于ACE抑制剂治疗的抗利尿激素分泌异常综合征所致。

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