β2-肾上腺素能受体的诱变：结构如何阐明功能 - Suppr

Suppr

超能文献

Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function.

作者信息

Ostrowski J, Kjelsberg M A, Caron M G, Lefkowitz R J

机构信息

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.

出版信息

Annu Rev Pharmacol Toxicol. 1992;32:167-83. doi: 10.1146/annurev.pa.32.040192.001123.

DOI:10.1146/annurev.pa.32.040192.001123

PMID:1318669

Abstract

摘要

相似文献

Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function.β2-肾上腺素能受体的诱变：结构如何阐明功能

Annu Rev Pharmacol Toxicol. 1992;32:167-83. doi: 10.1146/annurev.pa.32.040192.001123.

Structure and function of the beta 3-adrenergic receptor.β3肾上腺素能受体的结构与功能

Annu Rev Pharmacol Toxicol. 1997;37:421-50. doi: 10.1146/annurev.pharmtox.37.1.421.

Separation of the structural requirements for agonist-promoted activation and sequestration of the beta-adrenergic receptor.β-肾上腺素能受体激动剂促进激活和隔离的结构要求的分离。

Mol Pharmacol. 1990 Jun;37(6):775-9.

Beta-adrenergic receptors. Relationship of primary structure, receptor function, and regulation.β-肾上腺素能受体。一级结构、受体功能与调节的关系。

Am Rev Respir Dis. 1990 Feb;141(2 Pt 2):S22-30.

Structure and function of G protein-coupled receptors.G蛋白偶联受体的结构与功能。

Annu Rev Biochem. 1994;63:101-32. doi: 10.1146/annurev.bi.63.070194.000533.

Role of the beta-adrenergic receptor kinase in desensitization of the alpha 2-adrenergic receptor.

Trans Assoc Am Physicians. 1991;104:40-7.

Agonist interactions with chimeric and mutant beta1- and beta3-adrenergic receptors: involvement of the seventh transmembrane region in conferring subtype specificity.激动剂与嵌合及突变型β1和β3肾上腺素能受体的相互作用：第七跨膜区在赋予亚型特异性中的作用。

Mol Pharmacol. 1998 May;53(5):856-61.

Beta-adrenergic receptor regulation. New insights on biochemical and molecular mechanisms.β-肾上腺素能受体调节。关于生化和分子机制的新见解。

Receptor. 1990;1(1-2):13-32.

Amino acid substitutions at position 312 in the seventh hydrophobic segment of the beta 2-adrenergic receptor modify ligand-binding specificity.

Mol Pharmacol. 1993 Jul;44(1):111-4.

Structure-function analysis of the three beta-adrenergic catecholamine receptors.

Psychopharmacol Ser. 1993;10:9-14. doi: 10.1007/978-3-642-78010-3_2.

引用本文的文献

Get Ready to Sharpen Your Tools: A Short Guide to Heterotrimeric G Protein Activity Biosensors.准备好你的工具：异三聚体 G 蛋白活性生物传感器简介。

Mol Pharmacol. 2024 Aug 16;106(3):129-144. doi: 10.1124/molpharm.124.000949.

Role of Oxytocin/Vasopressin-Like Peptide and Its Receptor in Vitellogenesis of Mud Crab.类催产素/加压素肽及其受体在泥蟹卵黄发生中的作用。

Int J Mol Sci. 2020 Mar 26;21(7):2297. doi: 10.3390/ijms21072297.

Roles of Dopamine D₂ Receptor Subregions in Interactions with β-Arrestin2.多巴胺D₂受体亚区在与β-抑制蛋白2相互作用中的作用。

Biomol Ther (Seoul). 2016 Sep 1;24(5):517-22. doi: 10.4062/biomolther.2015.198.

Selectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific.CXCR6中DRF基序决定了Gi/o蛋白使用的选择性，且具有细胞类型特异性。

Mol Pharmacol. 2015 Nov;88(5):894-910. doi: 10.1124/mol.115.099960. Epub 2015 Aug 27.

The Camerino symposium series (1978-2013): a privileged observatory of receptorology development.卡梅里诺研讨会系列（1978 - 2013年）：受体学发展的特殊观测站

In Silico Pharmacol. 2013 Dec 20;1:21. doi: 10.1186/2193-9616-1-21. eCollection 2013.

Molecular Architecture of G Protein-Coupled Receptors.G蛋白偶联受体的分子结构

Drug Dev Res. 1996 Jan 1;37(1):1-38. doi: 10.1002/(SICI)1098-2299(199601)37:1<1::AID-DDR1>3.0.CO;2-S.

Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations.β2肾上腺素能受体两种不同失活构象的鉴定协调了结构与生化观察结果。

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4689-94. doi: 10.1073/pnas.0811065106. Epub 2009 Mar 3.

Molecular characterization and analysis of a truncated serotonin receptor gene expressed in neural and reproductive tissues of abalone.鲍鱼神经和生殖组织中表达的截短型血清素受体基因的分子特征及分析

Histochem Cell Biol. 2009 May;131(5):629-42. doi: 10.1007/s00418-009-0555-7. Epub 2009 Feb 13.

Agonist versus antagonist action of ATP at the P2Y4 receptor is determined by the second extracellular loop.ATP在P2Y4受体上的激动剂与拮抗剂作用由第二个细胞外环决定。

J Biol Chem. 2004 Mar 19;279(12):11456-64. doi: 10.1074/jbc.M301734200. Epub 2003 Dec 11.

Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin1A receptors from bovine hippocampus.二硫键和巯基在牛海马5-羟色胺1A受体激动剂和拮抗剂结合中的作用

Cell Mol Neurobiol. 2000 Dec;20(6):665-81. doi: 10.1023/a:1007046707845.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验