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症状性巨细胞病毒十二指肠炎症。艾滋病中的一个重要临床问题。

Symptomatic CMV duodenitis. An important clinical problem in AIDS.

作者信息

Wilcox C M, Schwartz D A

机构信息

Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303.

出版信息

J Clin Gastroenterol. 1992 Jun;14(4):293-7.

PMID:1318892
Abstract

Duodenal disease resulting from cytomegalovirus (CMV) infection is unusual in the absence of other gastrointestinal disease. We report two cases of CMV infection symptomatically isolated to the duodenum. One patient presented with ulcer-type dyspepsia, and the other with severe gastrointestinal bleeding. Ganciclovir therapy resulted in both a clinical and endoscopic remission. The importance of endoscopic evaluation is discussed given the necessity of mucosal biopsy for diagnosis and the availability of specific and effective therapy.

摘要

在没有其他胃肠道疾病的情况下,由巨细胞病毒(CMV)感染引起的十二指肠疾病并不常见。我们报告了两例症状性孤立于十二指肠的CMV感染病例。一名患者表现为溃疡型消化不良,另一名患者表现为严重的胃肠道出血。更昔洛韦治疗导致临床和内镜缓解。鉴于诊断需要进行黏膜活检以及有特异性有效治疗方法,本文讨论了内镜评估的重要性。

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Symptomatic CMV duodenitis. An important clinical problem in AIDS.症状性巨细胞病毒十二指肠炎症。艾滋病中的一个重要临床问题。
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[Gastrointestinal cytomegalovirus manifestations in AIDS].[艾滋病患者的胃肠道巨细胞病毒表现]
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Identification of distinctive clinical significance in hospitalized patients with endoscopic duodenal mucosal lesions.住院内镜十二指肠黏膜病变患者独特临床意义的识别
Korean J Intern Med. 2017 Sep;32(5):827-835. doi: 10.3904/kjim.2015.149. Epub 2017 Aug 21.
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A case of invasive cytomegalovirus duodenitis in an immunosuppressed patient 15 months after renal transplantation.肾移植后 15 个月,免疫抑制患者发生侵袭性巨细胞病毒十二指肠炎。
Infection. 2015 Jun;43(3):383-5. doi: 10.1007/s15010-014-0714-1. Epub 2015 Jan 13.
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Cytomegalovirus pseudotumor of the duodenum in a patient with AIDS: an unrecognized and potentially treatable clinical entity.
艾滋病患者十二指肠巨细胞病毒假瘤:一种未被认识到的潜在可治疗的临床实体。
Int J Infect Dis. 2010 Apr;14(4):e274-82. doi: 10.1016/j.ijid.2009.04.015. Epub 2009 Aug 19.
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Role of upper endoscopy in diagnosing opportunistic infections in human immunodeficiency virus-infected patients.上消化道内镜检查在诊断人类免疫缺陷病毒感染患者机会性感染中的作用。
World J Gastroenterol. 2009 Mar 7;15(9):1050-6. doi: 10.3748/wjg.15.1050.