Blanchot I, Dabadie A, Tell G, Guiguen C, Faugère B, Plat-Pelle A M, Roussey M
Service de pédiatrie-génétique médicale, CHU de Rennes, Pontchaillou, France.
Pediatrie. 1992;47(3):179-83.
A young Angolian boy who had emigrated to France at the age of 2, presented with a long history of fever. Gambian Trypanosomiasis was diagnosed with peculiar aspects: 1) evolution of adult sickness with a long hemolymphatic period (first stage) and a subacute worsening period with neurologic deficit and somnolence (second stage); 2) a possible post-transfusional contamination: the young boy, born in South Angola, a nor-highly endemic area, was transfused at the age of 10 months with the blood of a donor who was subsequently treated for Trypanosomiasis; 3) a suppurating adenopathy; 4) a predominance of IgG within the hypergammaglobulinemia while IgM are the predominant immunoglobulins in this affection; 5) a hepatic toxicity of Difluoromethylornithine.
一名2岁时移民到法国的安哥拉小男孩，有长期发热病史。冈比亚锥虫病被诊断出具有以下特殊情况：1）成人疾病的病程，有较长的血液淋巴期（第一阶段）以及伴有神经功能缺损和嗜睡的亚急性加重期（第二阶段）；2）可能存在输血后感染：这个小男孩出生在安哥拉南部，一个非高度流行地区，10个月大时接受了一名后来被诊断患有锥虫病的献血者的血液输血；3）化脓性腺病；4）高丙种球蛋白血症中以IgG为主，而在这种疾病中IgM是主要的免疫球蛋白；5）二氟甲基鸟氨酸的肝毒性。
