Meier J L, Straus S E
Medical Virology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892.
J Infect Dis. 1992 Aug;166 Suppl 1:S13-23. doi: 10.1093/infdis/166.supplement_1.s13.
The clinicoepidemiologic features of varicella-zoster virus and herpes simplex virus latency are clearly distinctive. These differences indicate that each virus has evolved a unique strategy to ensure the establishment and maintenance of latency and to reactive therefrom. Indeed, current data reveal divergent pathogenetic and molecular biologic properties that may account for the clinicoepidemiologic characteristics that distinguish recurrent infections with these herpesviruses.
水痘-带状疱疹病毒和单纯疱疹病毒潜伏的临床流行病学特征明显不同。这些差异表明，每种病毒都进化出了独特的策略来确保潜伏期的建立和维持，并从中重新激活。事实上，目前的数据揭示了不同的致病和分子生物学特性，这些特性可能解释了区分这些疱疹病毒复发性感染的临床流行病学特征。
