Chronic myocardial disease. II. Haemodynamic findings related to long-term prognosis.

Haemodynamic findings in 106 patients with chronic myocardial disease have been related to the course of the disease during a follow-up period of 2-12 years. A high filling pressure, especially when combined with low cardiac output, suggested a severe development. The worst outlook was noted in patients who in addition had raised pulmonary arteriolar resistance. On the other hand, a low filling pressure even if cardiac output was reduced, was generally associated with a more benign course. An increase in left ventricular wall thickness as determined angiographically suggested a better outlook than normal wall thickness.