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儿童腮腺上皮-肌上皮癌

Epithelial-myoepithelial carcinoma of the parotid gland in a child.

作者信息

Morinaga S, Hashimoto S, Tezuka F

机构信息

Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan.

出版信息

Acta Pathol Jpn. 1992 May;42(5):358-63. doi: 10.1111/j.1440-1827.1992.tb02886.x.

Abstract

A rare case of epithelial-myoepithelial carcinoma of the parotid gland, which occurred in a child, is reported. An 8-year-old boy presented with swelling of the right parotid gland. He underwent total parotidectomy followed by irradiation for a parotid gland tumor. Three years after the operation, a recurrent tumor invading the base of the skull and the brain and metastases in the lung were noted. The patient expired in spite of extirpation of the intracranial recurrent tumor. The resected tumor showed a characteristic histologic feature: double-layered tubular structures composed of inner dark cells (epithelial cells) and outer clear cells (myoepithelial cells). This patient may be the youngest one with the epithelial-myoepithelial carcinoma reported in the literature.

摘要

本文报道了一例罕见的发生于儿童的腮腺上皮-肌上皮癌。一名8岁男孩出现右侧腮腺肿大。他接受了腮腺全切术,随后针对腮腺肿瘤进行了放疗。术后三年,发现复发性肿瘤侵犯颅底和脑部,并出现肺部转移。尽管切除了颅内复发性肿瘤,患者仍死亡。切除的肿瘤显示出特征性的组织学特征:由内层暗细胞(上皮细胞)和外层透明细胞(肌上皮细胞)组成的双层管状结构。该患者可能是文献报道中患上皮-肌上皮癌的最年轻患者。

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