Horinouchi H, Ishihara T, Kawamura M, Kato R, Kikuchi K, Kobayashi K, Maenaka Y, Torikata C
Department of Surgery, Keio University School of Medicine, Japan.
J Clin Pathol. 1993 Feb;46(2):185-7. doi: 10.1136/jcp.46.2.185.
A case of epithelial myoepithelial tumour originating from the tracheal gland in a 57 year old woman is described. The tumour was removed by segmental tracheal resection and end-to-end anastomosis. Histologically, the tumour comprised clear cells and presented a monophasic pattern. Immunohistochemical analysis showed that the tumour cells were positive for both S-100 protein and smooth muscle actin. suggesting that this tumour resembles a subtype of epithelial-myoepithelial carcinoma described in the 1990 WHO international classification of salivary glands. Although some reports describe a clear cell dominant epithelial myoepithelial carcinoma, in this case local invasiveness or regional lymphnode metastasis was not proved through investigation. It is therefore concluded that this was an epithelial myoepithelial tumour rather than a carcinoma.
本文描述了一例57岁女性起源于气管腺的上皮肌上皮瘤。该肿瘤通过气管节段切除和端端吻合术切除。组织学上,肿瘤由透明细胞组成,呈单相模式。免疫组织化学分析显示肿瘤细胞S-100蛋白和平滑肌肌动蛋白均呈阳性,提示该肿瘤类似于1990年世界卫生组织唾液腺国际分类中描述的上皮-肌上皮癌的一种亚型。尽管一些报告描述了以透明细胞为主的上皮-肌上皮癌,但在本病例中,通过检查未证实有局部侵袭或区域淋巴结转移。因此得出结论,这是一例上皮肌上皮瘤而非癌。