Komissarova N V, Gomazkov O A
Biull Eksp Biol Med. 1976;81(4):390-2.
In vitro experiments showed that caoline-induced contact activation of the kallikreine-kinine system and streptokinase-induced activation of plasmin could possibly occur in rabbit blood plasma. Preliminary short-term treatment of plasma with chloroform removed the factor, inhibiting the two mentioned activation processes. The results obtained provided an indirect evidence for the existence of a functional relationship between the kallikreine and plasmin systems of the blood at the level of the initial step of their activation, i.e. the Hageman factor.
体外实验表明，胆碱诱导的激肽释放酶-激肽系统的接触激活以及链激酶诱导的纤溶酶激活可能在兔血浆中发生。用氯仿对血浆进行初步短期处理可去除抑制上述两种激活过程的因子。所得结果为血液中激肽释放酶系统和纤溶酶系统在其激活起始步骤水平（即Hageman因子）存在功能关系提供了间接证据。
