[沉淀抗胰激肽释放酶抗体对人及兔血液中精氨酸酯酶接触激活的影响]
[Effect of precipitating antibodies to pancreatic kallikrein on arginine esterase contact activation in human and rabbit blood].
作者信息
Karpitskiĭ V V, Guz S Ia
出版信息
Vopr Med Khim. 1979 May-Jun;25(3):242-5.
Effect of precipitating antibodies against pig pancreatic kallikrein on the BAEE-esterase activity was studied in human blood plasma and in rabbit blood serum, activated by kaolin. An inhibitory effect of the antibodies on the increased BAEE-esterase activity was observed within the first minute of incubation after treatment with kaolin. The inhibition of the BAEE-esterase activity constituted 65.1% in human blood plasma and 40.9% in rabbit serum. Possible mechanism is discussed on the inhibition of contact activation of arginine esterase in human and rabbit blood by antibodies against pancreatic kallikrein.
研究了抗猪胰激肽释放酶沉淀抗体对高岭土激活的人血浆和兔血清中BAEE - 酯酶活性的影响。在用高岭土处理后的孵育第一分钟内观察到抗体对BAEE - 酯酶活性增加有抑制作用。人血浆中BAEE - 酯酶活性的抑制率为65.1%，兔血清中为40.9%。讨论了抗胰激肽释放酶抗体抑制人和兔血液中精氨酸酯酶接触激活的可能机制。
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