对不育男性进行常规激素负荷试验并无必要。

Routine hormone load tests are unnecessary in infertile men.

作者信息

Gerhard I, Lenhard H K, Eggert-Kruse W, Runnebaum B

机构信息

Department of Gynecological Endocrinology, and Reproductive Medicine, Women's Hospital, University of Heidelberg, Germany.

出版信息

Andrologia. 1992 Jul-Aug;24(4):219-26. doi: 10.1111/j.1439-0272.1992.tb02641.x.

DOI:10.1111/j.1439-0272.1992.tb02641.x

PMID:1322641

Abstract

A sample of 225 men examined at the Infertility Service Unit of this hospital had spermiograms, standardized in accordance with WHO guide lines, and a hormone stimulation test with injection of gonadotropin releasing hormone, thyrotropin releasing hormone, and ACTH. The serum concentrations of the following hormones were assessed: follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, oestradiol (E), thyroid stimulating hormone, cortisol, 21-desoxycortisol, 17-hydroxypregnenolone, 17-hydroxyprogesterone, dehydroepiandrosterone, dehydroepiandrosteronesulphate, androstenedione, testosterone (T), and dihydrotestosterone. The results of the spermiograms were found to be related to the concentrations of the following hormones: FSH, LH, T, and E. Thyroid and adrenal function in men without signs of endocrinological diseases failed to influence spermatic parameters.

摘要

对在本院不育症服务科室接受检查的225名男性进行了精子图检查（按照世界卫生组织指南进行标准化），并进行了注射促性腺激素释放激素、促甲状腺激素释放激素和促肾上腺皮质激素的激素刺激试验。评估了以下激素的血清浓度：促卵泡激素（FSH）、促黄体生成素（LH）、催乳素、雌二醇（E）、促甲状腺激素、皮质醇、21-脱氧皮质醇、17-羟孕烯醇酮、17-羟孕酮、脱氢表雄酮、硫酸脱氢表雄酮、雄烯二酮、睾酮（T）和双氢睾酮。发现精子图结果与以下激素的浓度有关：FSH、LH、T和E。无内分泌疾病迹象的男性的甲状腺和肾上腺功能未对精子参数产生影响。