Chotmongkol V, Jitpimolmard S
Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
J Med Assoc Thai. 1992 Feb;75(2):85-8.
The results of an open study of the efficacy of oral itraconazole therapy in 8 patients with cryptococcal meningitis are reported. Therapy is monitored by clinical response with culture, indian ink stain and cryptococcal antigen testing of CSF. Four (50%) of eight patients were cured, two (25%) had partial response, and two (25%) failed. One patient had a relapse but responded to retreatment. No toxicity was observed. Itraconazole is, therefore, suggested as a new treatment for cryptococcal meningitis.
