Costello C, Webber A
Clin Genet. 1976 Jun;9(6):603-5. doi: 10.1111/j.1399-0004.1976.tb01619.x.
Neutrophil function was studied in 25 patients with Down's syndrome at a mental subnormality hospital and compared with 26 normal controls. In vitro killing of Candida albicans was significantly lower in the Down's group, but there was no difference in the percentage of cells actively involved in phagocytosis or in the phagocytic index. The spontaneous nitroblue tetrazolium reduction was increased in 10 patients, but no abnormality of peroxidase activity or leucocyte alkaline phosphatase activity was found.
在一家智力发育不全医院，对25名唐氏综合征患者的中性粒细胞功能进行了研究，并与26名正常对照者进行了比较。唐氏综合征组对白色念珠菌的体外杀伤能力明显较低，但在积极参与吞噬作用的细胞百分比或吞噬指数方面没有差异。10名患者的自发硝基蓝四唑还原反应增强，但未发现过氧化物酶活性或白细胞碱性磷酸酶活性异常。
