Bigsby R J, Lepp E K, Litwin D E, Wilkinson A A, Matte G G
Department of General Surgery, University of Saskatchewan, Saskatoon.
Can J Surg. 1992 Aug;35(4):388-92.
To compare the effectiveness of thallium chloride 201 and technetium 99m pentavalent dimercaptosuccinic acid in evaluating medullary carcinoma of the thyroid (MCT), eight patients with a history of MCT underwent imaging with both radiopharmaceuticals. Thallium 201 consistently gave superior images, as well as providing one less false-negative scan. Positive scans were obtained in patients with elevation of basal calcitonin levels to more than 1,000 ng/L. All of the patients with positive scans had clinical evidence of local recurrence. Improved imaging with thallium 201 was obtained by early scanning.
为比较氯化铊201和锝99m五价二巯基丁二酸在评估甲状腺髓样癌(MCT)中的有效性,8例有MCT病史的患者接受了这两种放射性药物的成像检查。铊201始终能提供更好的图像,且假阴性扫描少一次。基础降钙素水平升高至超过1000 ng/L的患者获得了阳性扫描结果。所有阳性扫描的患者均有局部复发的临床证据。通过早期扫描可获得铊201改善后的成像效果。