Chaudhry V, Glass J D, Griffin J W
Department of Neurology, Johns Hopkins Hospital, Baltimore, Maryland.
Neurol Clin. 1992 Aug;10(3):613-27.
This article first reviews the different classes of nerve injury. The temporal evolution of electrophysiologic changes occurring during Wallerian degeneration in humans is then described, followed by a description of sequential structural changes and cellular responses that occur after nerve transection. The final section focuses on the basis for resurgent research interest in Wallerian degeneration and the different research approaches being taken to answer basic science and clinical questions.
本文首先回顾了不同类型的神经损伤。接着描述了人类沃勒变性过程中发生的电生理变化的时间演变，随后阐述了神经横断后发生的一系列结构变化和细胞反应。最后一部分重点关注对沃勒变性重新产生研究兴趣的基础，以及为回答基础科学和临床问题所采用的不同研究方法。
