Bracchi O, Orazi E, Lupi G P, Bronzieri C, Cornalba L, Grassi C
Servizio di Nefrologia e Dialisi, Ospedale Predabissi, Melegnano, Italy.
Nephron. 1992;61(3):369-70. doi: 10.1159/000186948.
Hepatitis C virus (HCV) seems to be the most important agent of non-A, non-B hepatitis. This study was undertaken to assess the prevalence of hepatitis C in our renal unit. Twelve patients (29%) had antibodies against HCV (anti-HCV). Seropositive patients were on hemodialysis for a longer period than seronegatives. Statistically significant associations with anti-HCV were: blood transfusions, at least 1 episode of elevated value of transaminases (2-fold) and fluctuations of transaminases. Our findings confirm the high prevalence of anti-HCV in hemodialyzed patients, the importance of parenteral transmission and the high probability of liver disease in anti-HCV-positive patients.
丙型肝炎病毒(HCV)似乎是非甲非乙型肝炎的最重要病原体。本研究旨在评估我们肾科丙型肝炎的患病率。12名患者(29%)有抗丙型肝炎病毒抗体(抗-HCV)。血清阳性患者接受血液透析的时间比血清阴性患者长。与抗-HCV有统计学显著关联的因素有:输血、至少1次转氨酶值升高(2倍)以及转氨酶波动。我们的研究结果证实了血液透析患者中抗-HCV的高患病率、经肠外传播的重要性以及抗-HCV阳性患者发生肝病的高可能性。