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犬椎体骨髓炎磺胺类药物治疗相关的药疹

Drug eruption associated with sulfonamide treatment of vertebral osteomyelitis in a dog.

作者信息

Scott D W, Barrett R E, Tangorra L

出版信息

J Am Vet Med Assoc. 1976 Jun 15;168(12):1111-4.

PMID:132414
Abstract

Drug eruption was diagnosed in a 4-year-old German Shepherd Dog being treated with sulfonamides for vertebral osteomyelitis due to infection with Nocardia spp. The eruption was characterized by generalized, pruritic, eczematous dermatitis. Diagnosis was based on a history of repeated exposure to sulfonamides, skin biopsy findingd, and clinical recovery on cessation of sulfonamide therapy.

摘要

一只4岁的德国牧羊犬因诺卡氏菌属感染导致脊椎骨髓炎而接受磺胺类药物治疗,被诊断为药疹。皮疹的特征为全身性、瘙痒性、湿疹性皮炎。诊断依据为反复接触磺胺类药物的病史、皮肤活检结果以及停用磺胺类药物治疗后的临床康复情况。

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引用本文的文献

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An in vitro investigation of predisposition to sulphonamide idiosyncratic toxicity in dogs.犬类对磺胺类药物特异质性毒性易感性的体外研究。
Vet Res Commun. 1990;14(3):241-52. doi: 10.1007/BF00347744.